Current Clinical Trials

Clinicians at Eisenhower Medical Center continue to take part in groundbreaking research, including: interventional cardiology, orthopedics, novel biotherapies in oncology, targeted therapies base on molecular profile of cancer, early detection of cancer via specialized imaging, drugs aimed at improving survival of HIV patients, and use of integrative therapies to reduce side effects related to cancer treatment.

TypeDescriptionEnrollmentMore Info
CancerA011502 A Randomized Phase III Double Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for Node Positive HER2 Negative Breast Cancer: The ABC TrialOpenMore Info
CancerA081105 Randomized Double Blind Placebo Controlled Study of Erlotinib or Placebo in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NSCLC)OpenMore Info
CancerA151216 Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST) OpenMore Info
CancerE2112 A Randomized Phase III Trial of Endocrine Therapy Plus Entinostat/Placebo in Patients With Hormone Receptor-Positive Advanced Breast CancerOpenMore Info
CancerE3A06 Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma.OpenMore Info
CancerE4512 A Phase III Double-Blind Trial for Surgically Resected Early Stage Non-small Cell Lung Cancer: Crizotinib Versus Placebo for Patients With Tumors Harboring the Anaplastic Lymphoma Kinase (ALK) Fusion ProteinOpenMore Info
CancerEA2142 Randomized Phase II Study of Cisplatin and Etoposide Versus Temozolomide and Capecitabine in Patients With Advanced G3 Non-small Cell Gastroenteropancreatic Neuroendocrine CarcinomasOpenMore Info
CancerEA5142 Adjuvant Nivolumab in Resected Lung Cancers (ANVIL)-A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-small Cell Lung CancersOpenMore Info
CancerEA8143 A Phase 3 RandOmized Study Comparing PERioperative Nivolumab vs. Observation in Patients With Localized Renal Cell Carcinoma Undergoing Nephrectomy (PROSPER RCC)OpenMore Info
CancerEAY131 Molecular Analysis for Therapy Choice (MATCH) OpenMore Info
CancerLung Cancer Detection Program Using Computerized Tomography. I-ELCAP at Eisenhower Lucy Curci Cancer Center.OpenMore Info
CancerMulti-center Prospective Evaluation of the Clinical Utility of Endoscopic Submucosal Dissection (ESD) in the Western Population OpenMore Info
CancerNRG-BR003 A Randomized Phase III Trial of Adjuvant Therapy Comparing Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel With or Without Carboplatin for Node-Positive or High-Risk Node-Negative Triple-Negative Invasive Breast CancerOpenMore Info
CancerNRG-GU002 Phase II-III Trial of Adjuvant Radiotherapy Following Radical Prostatectomy With or Without Adjuvant Docetaxel OpenMore Info
CancerRTOG-0924: Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole-Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized TrialOpenMore Info
CancerS1207 Phase III Randomized, Placebo-Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy +/- One Year of Everolimus in Patients with High-Risk, Hormone Receptor-Positive and HER2/NEU Negative Breast Cancer. e3 StudyOpenMore Info
CancerS1320 A Randomized, Phase II Trial of Intermittent Versus Continuous Dosing of Dabrafenib (NSC-763760) and Trametinib (NSC-763093) in BRAFV600E/K Mutant MelanomaOpenMore Info
CancerS1400 Lung-MAP: Biomarker-Targeted Second-Line Therapy in Treating Patients With Recurrent Stage IV Squamous Cell Lung Cancer. A Phase II/III Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (Lung-MAP) OpenMore Info
CancerS1403 A Randomized Phase II/III Trial of Afatinib Plus Cetuximab Versus Afatinib Alone in Treatment-Naive Patients With Advanced, EGFR Mutation Positive Non-small Cell Lung Cancer (NSCLC)OpenMore Info
CancerS1416 Phase II Randomized Placebo-Controlled Trial of Cisplatin With or Without ABT-888 (Veliparib) in Metastatic Triple-Negative Breast Cancer and/or BRCA Mutation-Associated Breast CancerOpenMore Info
CancerS1513 Randomized Phase II Study of 2nd Line FOLFIRI Versus Modified FOLFIRI With PARP Inhibitor ABT-888 (Veliparib) (NSC-737664) in Metastatic Pancreatic CancerOpenMore Info
CancerS1605 Phase II Trial of Atezolizumab in BCG-Unresponsive Non-muscle Invasive Bladder Cancer OpenMore Info
CancerS1609 DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors OpenMore Info
CancerStudy of the Health Effects of Secondhand Smoke Exposure on Never Smokers. FAMRI-IELCAP study.OpenMore Info
CancerUCSD PREDICT - Profile Related Evidence Determining Individualized Cancer Therapy aka Study of Personalized Cancer Therapy to Determine Response and Toxicity OpenMore Info
CancerE1609 A Phase III Randomized Study of Adjuvant Ipilimumab Anti-CTLA4 Therapy Versus High-Dose Interferon a-2b for Resected High-risk Melanoma ClosedMore Info
CancerE5103 A Double Blind Phase III Trial of Doxorubicin and Cyclophosphomide followed by Pacilitaxel with Bevacizumab or PlaceboClosedMore Info
CancerE5202 A Randomized Phase III Study Comparing 5-FU, Leucovorin and Oxaliplatin vs 5-FU, Leucovrin, Oxaliplatin and Bevacizumab in Patients w/ Stage II Colon Cancer at High Risk for Recurrence to Determine Prospectively Prognostic Value of Molecular MarkersClosedMore Info
CancerE5597 Phase III Chemoprevention Trial Selenium Supplementation in Persons with Resected Stage 1 Non-Small Cell Lung Cancer ClosedMore Info
CancerIBCSG-24-02 A Phase III Trial Evaluating the Role of Ovarian Function Suppression and the Role of Exemestane as Adjuvant Therapies for Premenopausal Women with Endocrine Responsive Breast Cancer (SOFT)ClosedMore Info
CancerNSABP B-42 A Clinical Trial to Determine the Efficacy of 5 Years of Letrozole Compared to Placebo in Patients Completing 5 Years of Hormonal Therapy Consisting of an Aromatase Inhibitor or Tamoxifen Followed by an AI in Prolonging Disease-free survivalClosedMore Info
CancerNSABP B-47 A Randomized Phase III Trial of Adjuvant Therapy Comparing Chemo Alone (6 Cycles of AC or 4 Cycles of AC followed by Weekly Paclitaxel) to Chemo + Trastuzumab in Women w/Node-Positive or High-Risk Node-Negative HER2-Low Invasive Breast CancerClosedMore Info
CancerNSABP P-5 Phase III Randomized Study of Adjuvant Rosuvastatin in Patients with Resected Stage I or II Colon Cancer. A Statin Polyp Prevention Trial in Patients With Resected Colon CancerClosedMore Info
CancerNSABP-B-38 Phase III Randomized Study of three Different Adjuvant Chemotherapy Regimens Comprising Docetaxel, Doxorubicin, and Cyclophosphamide Versus Dose-Dense Doxorubicin, Cyclophosphamide, and Paclitaxel Versus Dose-Dense Doxorubicin, CyclophosphamideClosedMore Info
CancerRandomized Control Trial Evaluating the Effects of Inhaled Aromatherapy on Nausea and Vomiting in Patients with Cancer Receiving Treatment in an Outpatient Cancer CenterClosedMore Info
CancerREVEAL Prospective Observational Study of Patients with Polycythemia Vera in US clinical PracticesClosedMore Info
CancerS0424 Carcinogens in Lung Tissue From Smokers and Non-Smokers With Newly Diagnosed Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer. Molecular Epidemiology Case-Series of NSCLC in Smokers and Non-Smokers.ClosedMore Info
CancerS0820 A Double Blind Placebo-Controlled Trial of Eflornithine & Sulindac to Prevent Recurrence of High Risk Adenomas and Second Primary Colorectal Cancers in Patients With Stage 0-III Colon or Rectal CancerClosedMore Info
CancerS0931 EVEREST: EVErolimus for Renal Cancer Ensuring Surgical Therapy, A Phase III StudyClosedMore Info
CancerSCUSF-0806 Phase II placebo-controlled trial of lisinopril and Coreg CRClosedMore Info
CardiacGOULD - Getting to an Improved Understanding of Low-Density Lipoprotein Cholesterol and Dyslipidemia Management: A Registry of High Cardiovascular Risk in Subjects in the United StatesOpenMore Info
CardiacMedtronic Product Surveillance RegistryOpenMore Info
CardiacPLEXA ICD Lead RegistryOpenMore Info
CardiacSentus QP-Extended CRT Evaluation with Quadripolar Left Ventricular Leads - QP ExCELsOpenMore Info
CardiacA Clinical Evaluation of the Diagnostic Utility of MRI Scans in Patients Implanted with St. Jude Medical Pacemakers, Implantable Cardioverter Defibrillator and Cardiac Resynchronization Therapy DevicesClosedMore Info
CardiacAccent Magnetic Resonance Imaging Pacemaker and Tendril Magnetic Resonance Imaging™ Lead Investigational Device Exemption StudyClosedMore Info
CardiacCardioMEMS™ HF System Post Approval StudyClosedMore Info
CardiacCardiovascular Implantable Electroic Device (CIED) Antibiotic Envelope Infection Prevention Trial: WRAP-ITClosedMore Info
CardiacCELESTIAL Post Approval Registry: Corox OTW, Endocardial, Left Ventricular Steroid Lead, Bipolar Post Approval RegistryClosedMore Info
CardiacINGEVITY™ Active Fixation and Passive Fixation Pace/Sense Lead Clinical StudyClosedMore Info
Emergency MedicineExtremity Exsanguination Device™ for Systolic Blood Pressure < 80 mmHg OpenMore Info
Emergency MedicineHemodynamic Effects of Extremity Exsanguination Device (EED) and ZOEX Anti-Shock Trousers in Mildly Dehydrated Healthy Volunteers.OpenMore Info
HIVACTG A5332/REPRIEVE - A Randomized Trial to Prevent Vascular Events in HIV. Sponsored by the AIDS Clinical Trial Group (ACTG), Division of AIDS (DAIDS), NIAID, National Institute of Health (NIH)OpenMore Info
HIVATLAS-Antiretroviral Therapy as Long Acting Suppression. Evaluating the Efficacy, Safety, & Tolerability of Switching to Long-acting Cabotegravir + Long-acting Rilpivirine From Current Antiretroviral Regimen in Virologically Suppressed HIV-1+ AdultClosedMore Info
HIVGS-1844 A Phase 3, Randomized, Double-Blind Study to Evaluate Safety and Efficacy of Switching from a Regimen of Dolutegravir and ABC/3TC, or a Fixed Dose Combo (FDC) or ABC/DTG/3TC to a FDC of GS-9883/F/TAF in Virologically Supressed HIV+ SubjectsClosedMore Info
HIVGS-1878 A Phase 3, Randomized, Open-Label Study to Evaluate the Safety & Efficacy of Switching from Regimens of Boosted Atazanavir or Darunavir + either Emtricitabine/Tenofovir of Abacavir/Lamivudine to GS-9883/Emtricitabine/Tenofovir AlafenamideClosedMore Info
Infectious DiseaseTOUR - Telavancin Observational Use Registry OpenMore Info
NeurologyPOINT (Platelet-Oriented Inhibition in New TIA or Minor Stroke)OpenMore Info
NeurologyThe Impact of Smartphone Technology for Interprofessional Patient Care Communication in the Emergency Department and the Critical Care UnitsOpenMore Info
NeurologyUsability Study for Electronic Wrist Splint for Treatment of Carpal Tunnel DiseaseOpenMore Info
NeurologyImaging Dementia—Evidence for Amyloid Scanning (IDEAS) Study: A Coverage with Evidence Development Longitudinal Cohort StudyOpenMore Info
NursingCancer patients' expectations and recommendations concerning suspension of the do-not-resuscitate (DNR) order during the perioperative period if patients were to have surgeryOpenMore Info
NursingThe Relationship between Organizational Empowerment, Personal Nurse Empowerment and Patient Empowerment in an Acute Care Hospital With Magnet Designation versus a Non-Magnet Designated HospitalOpenMore Info
NursingPilot Study of the Effects of Smartphone Technology on Interprofessional Patient Care CommunicationClosedMore Info
OrthopedicCorrelation Between Anterior Cruciate Ligament Reconstruction Surgery and Early Onset Total Knee ReplacementOpenMore Info
OrthopedicAmerican Joint Replacement RegistryOpenMore Info
OrthopedicEfficacy of the BioWick SureLock Impalnt for the Reattachment of Soft Tissue to Bone in Subjectys UIndrgoing Rotator Cuff RepairsOpenMore Info
OrthopedicPathogenesis of Rheumatic DiseaseOpenMore Info
OrthopedicPost-Approval Observational Data Collection Study on the Conventus Cage(TM) PH for use in Proximal Humerus Fracture Fixation OpenMore Info
OrthopedicUse of Foot Muscle Strengthening to Treat Plantar FasciitisOpenMore Info
OrthopedicA Prospective, Multicenter Study of Instrumented Posterolatral Lumbar Fusion (PLF) with OsteoAMP to Evaluate Long-Term safety and Efficacy in Patients Requiring 1-2 Level Instrumented PLFClosedMore Info
OrthopedicA Randomized, Prospective, Comparative Study of Acupuncture and Post-Operative Pain Management with Shoulder ArthroplastyClosedMore Info
OrthopedicPost-Market 10 year follow up of Mobi-C Cervical Disc for one and two level treatment of cervical disc diseaseClosedMore Info
OrthopedicRetrospective Review of Functional Results of Reverse Total Shoulder ArthroplastyClosedMore Info
OrthopedicThe Investigational Plan for the Evaluation of the ACADIA Facet Replacement System (Pivotal IDE Trial)ClosedMore Info
OtherAn Analysis of the Effectiveness of a Palliative Care Program OpenMore Info
OtherCaring for the Caregivers: A Lifestyle Intervention for Those Caring for Patients with DementiaOpenMore Info
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